Iyini i-peptide?

I-Peptide ibhekisela ohlotsheni lwenhlanganisela okwakheka kwayo kwamangqamuzana phakathi kwe-amino acid namaprotheni, Yakhiwa izinhlobo ezingama-20 zama-amino acid emvelo ekwakhiweni nasekuhleleni okuhlukene, ukusuka kuma-dipeptides kuye kuma-polypeptides esakhiwo esiyinkimbinkimbi noma esiyindilinga.Yonke i-peptide inesakhiwo sayo esiyingqayizivele, futhi ukwakheka kwama-peptide ahlukene kuncike emsebenzini wawo.I-Peptide inokulandelela okuqukethwe emzimbeni webhayoloji, kodwa inomsebenzi oyingqayizivele wokuphila.Phakathi kwazo, ama-peptide angalawula ukusebenza komzimba okubizwa ngokuthi i-peptide esebenzayo noma i-peptide esebenzayo.Ekuqaleni kwe-20^thNgekhulu leminyaka, impumelelo yokuhlanganisa amakhemikhali i-dipeptide ikhombisa ukubonakala kwesayensi ye-peptide.

Amaqiniso amaningi afakazela ukuthi amaprotheni awakwazi ukumunca kuphela ngesimo se-amino acid, kodwa futhi amunca ezinhlotsheni eziningi zama-peptide.Ngokuvamile kunenkolelo yokuthi ama-dipeptides nama-tripeptides adonswa kumaseli amathumbu bese efakwa nge-hydrolyzed nge-peptidase ukuze angene ekujikelezeni kwegazi ngendlela yama-amino acid amahhala.Isithwali se-peptide singena ekujikelezeni.

Ucwaningo luphinde lwathola ukuthi amaprotheni agaywe umzimba womuntu ayagaywa futhi amuncwa ngendlela yama-oligopeptides ngemuva kokusebenza kwama-enzyme emgudwini wokugaya ukudla, futhi ingxenye yokumuncwa ngendlela yama-amino acid amahhala incane kakhulu.

Amaprotheni amuncwa ngendlela ye-peptide, engagwemi nje kuphela ukuncintisana phakathi kwama-amino acid, kodwa futhi enciphisa umphumela ophambene wengcindezi ephezulu ye-osmotic emzimbeni womuntu.Ngakho-ke, ukuhlinzeka ngezinto ezinomsoco emzimbeni womuntu ngendlela ye-peptide kuhle ekusebenziseni ngokushesha umphumela wokusebenza kwe-peptide.Ngaphezu kwalokho, i-valence yebhayoloji kanye nenani lokudla okunempilo kwe-peptide liphezulu kunama-amino acid amahhala.Ngakho-ke, i-collagen peptide isiphenduke indawo entsha eshisayo emkhakheni wocwaningo lokudla okunempilo kwamaprotheni, futhi i-peptide encane yamangqamuzana noma i-oligopeptide yenza ukudla komlomo okunempilo kunesisekelo sesayensi.