I-collagen iyiphrotheni eningi kakhulu ezilwaneni, ibalwa ku-70% wamaprotheni esikhumba somuntu.Ku-dermis, i-collagen yakha inethiwekhi nezinye izinto ezisiza isikhumba ukuba sizinze ukwakheka kwaso, amandla, nokunwebeka.Njengamanje, kunezifundo eziningi zokwenza ngcono isikhumba ngama-peptide omlomo we-collagen.Kutholakala ukuthi i-collagen peptide yomlomo ingathuthukisa izimo zesikhumba, inciphise imigqa ye-beryllium, ikhulise umswakama wesikhumba, ilungise isikhumba esonakele, futhi ibambezele ukuguga.

Indlela eyinhloko ukuthi ngemva kokuthatha ama-peptide e-collagen, ingakhuphula ukubonakaliswa kwe-collagen esikhumbeni, inciphise umsebenzi we-matrix metalloproteinase 2, futhi ithinte ukwanda kwe-fibroblasts kanye nokwakheka kwe-collagen fibers ngendlela yamaprotheni athile.

Inhloso:

Ama-collagen peptideszisetshenziswa kabanzi emhlabeni wonke njengohlobo olusha lwesithako sokudla esisebenzayo.Ama-Collagen peptide avame ukubizwa nge-collagen emakethe, okuwumkhiqizo okhiqizwa yi-enzymatic hydrolysis yesikhumba sesilwane, amathambo, izikali nezinye izingxenye.Ngenxa yezizathu ezifana nezifo zezilwane kanye nezinkolelo zenkolo, izinhlanzi zasolwandle i-collagen peptide zithandwa kakhulu phakathi kwabathengi.

Indlela:

Imibandela yokufakwa yezifundo zokuhlolwa: Amavolontiya afanelekayo angu-35, aneminyaka engu-30-50 ubudala.Ngaphambi kokuqala kokuhlolwa, wonke amavolontiya asayine imvume enolwazi.

Imibandela yokukhishwa: ① Labo abaye bathola ukwelashwa ebusweni phakathi nezinyanga ezimbili;② Labo abaphuze izidakamizwa noma imikhiqizo yezempilo ehlobene nomsebenzi wokuhlola phakathi nenyanga eyodwa, okuzothinta ukwahlulela kwemiphumela;③ Abesifazane abakhulelwe noma abancelisa;④ Iziguli zengqondo, imilutha yotshwala nezidakamizwa;⑤ iziguli ezinezifo zesistimu noma izifo zesikhumba ezinzima;⑥ abantu abanomlando wokungezwani nemikhiqizo yezempilo nokunye okungaphatheki kahle komzimba;

Hlola ikakhulukazi umswakama wesikhumba, uwoyela nokunwebeka;i-visia digital skin analyzer (USA), ihlola ikakhulukazi izinkomba eziyi-8 zamabala esikhumba, imibimbi, izimbotshana, ukuthungwa, i-porphyrin ensomi, amabala e-ultraviolet, amabala ansundu, nezindawo ezibomvu.

Umphumela:

Imiphumela yokuhlolwa kwe-Visia: Ngemva kokuphathwa ngomlomo kwe-cod skin collagen oligopeptides, imibimbi yesikhumba, ukuthungwa, izimbotshana, izindawo ezibomvu, i-porphyrin onsomi, umswakama, namafutha eqenjini lokuhlola kwathuthukiswa kakhulu, futhi kwaba nomehluko omkhulu uma kuqhathaniswa nalawo angaphambi kokuhlolwa. kanye neqembu lokulawula ( P<0.05);Amachashaza, amabala e-ultraviolet, namachashaza ansundu kuye kwathuthukiswa kancane, kodwa kwakungekho mehluko omkhulu uma kuqhathaniswa nangaphambi kokuphakelwa kanye neqembu lokulawula (P>0.05);izinkomba zesikhumba zeqembu lokulawula zazingenazo izinguquko ezibalulekile ngaphambi nangemva kokuhlolwa (P>0.05).

Kungabonakala emfanekisweni wokuthi ngemva kokuphathwa komlomo weI-cod skin collagen oligopeptides, umswakama wesikhumba kanye nenani le-elasticity yeqembu lokuhlola lenyuka, futhi okuqukethwe kwe-sebum kwehla, okwakuhluke kakhulu kulokho ngaphambi kokuphathwa komlomo (P<0.05).

Isifinyezo:

Kulolu cwaningo, umswakama wesikhumba, i-sebum, i-elasticity, imibimbi, ukuthungwa, ama-pores, indawo ebomvu, nezinkomba ze-porphyrin zeqembu lokuhlola zathuthukiswa kakhulu, ezihambisana nezifundo zangaphambilini.Lokhu kungase kube ngenxa yokuthi lo mkhiqizo ucebile ngama-oligopeptides e-collagen aphansi, angakhuphula okuqukethwe kwe-collagen ku-dermis, athuthukise ukwakheka kwesikhumba, futhi akhuthaze umzimba wesikhumba.

Ekuhlolweni kwe-Visia, amabala, amabala e-ultraviolet, namachashaza ansundu eqembu lokuhlola athuthukisiwe, kodwa umehluko wezibalo wawungabalulekile.Kungase kube isikhathi sokuhlola kwakuyinyanga engu-1 kuphela, futhi ukuthuthukiswa kwe-photodamage kwakungabonakali, okuhambisana nemiphumela yangaphambilini yesazi sase-Danish u-Kieffer et al.Imiphumela yokuhlola ibonise ukuthi ngemva kwezinyanga ezingu-6 zokuphathwa ngomlomo kwama-collagen peptides, i-echo kanye nokuminyana kwe-papillary dermis kanye ne-reticular dermis yesikhumba esilimele kwanda.

Ngaphezu kwalokho, lolu cwaningo luphinde lwenze uhlu lwemibuzo, futhi imiphumela yabonisa ukuthi amandla omzimba, ukulala kanye nesikhumba seqembu lokuhlola kwathuthukiswa, okungenzeka kungenxa yokuthi i-collagen peptide inemiphumela yokuthuthukisa ukungatheleleki kanye ne-anti-oxidation.

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